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Avalon | 02-20-2009 08:26 AM
expiration dates on drugs since some here are storing drugs I thought this might be of interest. The expiration date on the manufacturer's package is based on the stability of the drug in its original closed container. The date does not necessarily mean that the drug was found to be unstable after a longer period; it means only that real-time data or extrapolations from accelerated degradation studies indicate that the drug will still be stable at that date. The expiration date for new drugs is usually 2-3 years from the date of manufacture. Once the original container is opened for use or dispensing, the expiration date on the container no longer applies. Retail pharmacists who repackage drugs, in accordance with the standards of the US Pharmacopoeia (USP), label them with a "beyond-use" date generally one year from the date the prescription is filled. The only report of human toxicity that may have been caused by chemical or physical degradation of a pharmaceutical product is renal tubular damage that was associated with use of degraded tetracycline (GW Frimpter et al, JAMA 1963; 184:111). Stability: Shelf life is the time a product, stored under reasonable conditions, is expected to remain stable (generally retain >90% of potency) (B Kommanaboyina and CT Rhodes, Drug Dev Ind Pharm 1999; 25:857). Data from the Department of Defense/FDA Shelf Life Extension Program, which tests the stability of drug products past their expiration date, showed that 84% of 1122 lots of 96 different drug products stored in military facilities in their unopened original containers would be expected to remain stable for an average of 57 months after their original expiration date (JS Taylor et al, 2002 FDA Science Forum Poster Abstract, Board AC-08, www.fda.gov, search 2002 FDA science forum). Source(s): http://www.byui.edu/healthcenter/faq/7.h...

elroy | 02-20-2009 07:45 PM
Re: expiration dates on drugs Thanks for the info. We just got a big bottle of amoxicillin. It is dated 24 months to expiration.

Jodster71 | 02-21-2009 01:51 AM
Re: expiration dates on drugs I used to work in a Tylenol plant at I can tell you they test their drugs at the extremes of storage. For example Tylenol lots were stored in what was called the "louisiana Room". The purpose of the room was to simulate an unconditioned medicine cabinet in Louisiana . . one of the hottest and humid locations in America. At certain sample periods a box of product would be removed from the room and tested for "efficacy", the effectiveness of its medical components. In the case of Tylenol, it is still a highly effective and safe drug YEARS after the expiry date even in harsh storage conditions. I'd give it half a decade in cool and dry conditions. . easily!

ImaCannin | 02-21-2009 01:54 AM
Re: expiration dates on drugs Hubby just read something about this, and that meds are good for many years!

mick silver | 02-21-2009 02:01 AM
Re: expiration dates on drugs do any of you store your meds inthe ref , it help it last longer

SAUM | 02-21-2009 07:52 AM
Re: expiration dates on drugs Just a thought. My ex was charged with "possessing dangerous drugs without a prescription". She is bi-polar and was drunk, acting like an ass, and had it coming however, that charge leads me to wonder if our good protectors could charge you during a raid for scripts out of date. I don't intend to get raided and I do have a large stash of amoxicillian but it is something to think about.

beercritic | 02-21-2009 08:01 AM
Re: expiration dates on drugs I've never found Tylenol to be effective at ANYTHING. Never alleviated any pain or discomfort unless it was accompanied by narcotics. Just a placebo, IMO. Oh, and toxic to kidneys.

hypervel | 02-21-2009 12:02 PM
Re: expiration dates on drugs I tend to rely on Ibuprophen, got a lot of it just in case. Thanks, Av for the research. This was the study I recall seeing before-my concern is that "-cillins" are bio based and possibly less shelf stable than one might hope. Think Aspirin, and that Vinegar smell when it goes bad. freezing = good?

End of Hope | 02-21-2009 02:19 PM
Re: expiration dates on drugs Expiration dates = the influence of lawyers and politicians. Most products are not dangerous or even unusable after the labeled expiration dates (though slightly diminishment of effect or taste occurs). For example, bottle water is "expired" two years after manufacture, but if stored correctly, it will last many more years than that. Same with almost all pharmaceuticals. Oxidation, light, and heat are the main problems, so keep the oxygen, light, and heat away, and the pharmaceutical will last beyond the expiration date.

End of Hope | 02-21-2009 02:22 PM
Re: expiration dates on drugs Quote:
Originally Posted by SAUM (Post 1584596) Just a thought. My ex was charged with "possessing dangerous drugs without a prescription". She is bi-polar and was drunk, acting like an ass, and had it coming however, that charge leads me to wonder if our good protectors could charge you during a raid for scripts out of date. I don't intend to get raided and I do have a large stash of amoxicillian but it is something to think about.
Does anyone have hard info on drug laws regarding issuance of prescriptions as relates to keeping legally-issued prescriptions after expiration date? This sounds insane, but, with government, that may not be a surprise.

End of Hope | 02-21-2009 02:23 PM
Re: expiration dates on drugs Quote:
Originally Posted by beercritic (Post 1584600) I've never found Tylenol to be effective at ANYTHING. Never alleviated any pain or discomfort unless it was accompanied by narcotics. Just a placebo, IMO. Oh, and toxic to kidneys.
Acetaminophen (Tylenol, aka APAP/Paracetamol) is mostly toxic to the liver.

Twisted Avatar | 02-21-2009 02:33 PM
Re: expiration dates on drugs Someone around here posted a story about this and gave an example that left me slack jawed. The Deparment of Defense they had something like 2 million doses of Penicillin from the vietnam era....... that were stored in the most haphazard of ways (think ammo can type storage for 40 plus years) A major Pharma company was trying push them to make another huge antibiotic purchase when the DOD declined the Pharma company requested that a efficacy test be done on the milsurp and there product. When the tests came back The 40 year or milsurp was more potent then the stuff they where trying to sell to the DOD!!! If stored in a cool dry place Meds will almost last as long as ammo. expiration dates are placed on products to justify new purchases. T

GreenSpirit | 02-21-2009 02:37 PM
Re: expiration dates on drugs Keep your spiritual practices strong, learn to breathe properly, include raw garlic in your diet and you can throw away the antibiotics.:shine:

RealityCheck | 02-21-2009 07:13 PM
Re: expiration dates on drugs edit: nevermind.:)

beercritic | 02-22-2009 09:49 AM
Re: expiration dates on drugs Quote:
Originally Posted by End of Hope (Post 1585029) Acetaminophen (Tylenol, aka APAP/Paracetamol) is mostly toxic to the liver.
Thanks. I stand corrected.

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